QuartzComposer is really complicated and doing basic things as a drop shadow takes ages, Adobe Edge is nice but it won't let you work on big compositions for retina devices (due to the fact that you can't zoom out more than 50%). It is not easy to make modifications in AfterEffects but it gives you a lot of freedom and nice acceleration features.
I would go for AfterEffects.
QuartzComposer is really complicated and doing basic things as a drop shadow takes ages, Adobe Edge is nice but it won't let you work on big compositions for retina devices (due to the fact that you can't zoom out more than 50%). It is not easy to make modifications in AfterEffects but it gives you a lot of freedom and nice acceleration features.